If you have a Mac that uses an Intel processor you can use Parallels or BootCamp to run Windows.  You then run AirMail in the Windows environment on your Mac.  Parallels has the advantage that you don’t have to re-boot to switch operating systems.  See www.parallels.com.  BootCamp also works fine for Mac’s with Intel chips but does require re-booting to change between operating systems.  In both cases you need to have a copy of Windows.

Newer Mac computers that run on the M-series processors (e.g. M1, M2) processors are also supported by Parallels running Windows-ARM (bundled with Parallels) and happily run AirMail, but connecting a USB device requires ARM device drivers– which are not available at this time for the USB versions of the SCS Pactor modems (e.g. PTC-II/IIIusb, DR-7×00). Network-connected modems do not require drivers and should work (but are untested), Bluetooth may work but is also untested.  Older modems with a serial-port interface and a FTDI USB/serial adaptor should work with FTDI’s ARM drivers, other USB/serial adaptors will depend on ARM drivers.

Another approach to running AirMail on a Mac is to use the Mac version of WINE or Crossover. This approach allows running Windows programs without Windows, but again Apple’s switch to the M-series processors has changed things. And setup can be a challenge. For details on how to run AirMail on a Intel-processor Mac using WINE/Crossover see:   http://tritonmarinesystems.com/Media-Sailmail/       Thanks to Stas’ Lewak for this information.